![Foto de JESÚS MANUEL](/img/uploaded/55B9FC29095D7EED281CB9438E662D84.jpg)
JESÚS MANUEL
APARICIO FERNÁNDEZ
Catedrático de Universidad
Argitalpenak (66) JESÚS MANUEL APARICIO FERNÁNDEZ argitalpenak
2022
-
Modulation of Multiple Gene Clusters’ Expression by the PAS-LuxR Transcriptional Regulator PteF
Antibiotics, Vol. 11, Núm. 8
-
Understanding microRNAs in the Context of Infection to Find New Treatments against Human Bacterial Pathogens
Antibiotics, Vol. 11, Núm. 3
2021
-
Production, Detection, Extraction, and Quantification of Polyene Antibiotics
Methods in Molecular Biology (Humana Press Inc.), pp. 333-350
2020
-
Structural and bioactivity characterization of filipin derivatives from engineered streptomyces filipinensis strains reveals clues for reduced haemolytic action
Antibiotics, Vol. 9, Núm. 7, pp. 1-11
-
The Streptomyces filipinensis gamma-butyrolactone system reveals novel clues for understanding the control of secondary metabolism
Applied and Environmental Microbiology, Vol. 86, Núm. 18
2019
-
Activation of secondary metabolite gene clusters in streptomyces clavuligerusby the pimm regulator of streptomyces natalensis
Frontiers in Microbiology, Vol. 10, Núm. MAR
2018
-
Phosphate effect on filipin production and morphological differentiation in Streptomyces filipinensis and the role of the PhoP transcription factor
PLoS ONE, Vol. 13, Núm. 12
-
Promoter engineering reveals the importance of heptameric direct repeats for DNA binding by Streptomyces antibiotic regulatory protein- large ATP-binding regulator of the LuxR family (SARP-LAL) regulators in Streptomyces natalensis
Applied and Environmental Microbiology, Vol. 84, Núm. 10
2016
-
Biotechnological production and application of the antibiotic pimaricin: biosynthesis and its regulation
Applied Microbiology and Biotechnology, Vol. 100, Núm. 1, pp. 61-78
2015
-
Functional analysis of filipin tailoring genes from Streptomyces filipinensis reveals alternative routes in filipin III biosynthesis and yields bioactive derivatives
Microbial Cell Factories, Vol. 14, Núm. 1
-
Pathway-specific regulation revisited: cross-regulation of multiple disparate gene clusters by PAS-LuxR transcriptional regulators
Applied Microbiology and Biotechnology, Vol. 99, Núm. 12, pp. 5123-5135
2014
-
Erratum to: Genome-wide analysis of the regulation of pimaricin production in Streptomyces natalensis by reactive oxygen species (Applied Microbiology and Biotechnology DOI: 10.1007/s00253-013-5455-z)
Applied Microbiology and Biotechnology
-
Genome-wide analysis of the regulation of pimaricin production in Streptomyces natalensis by reactive oxygen species
Applied Microbiology and Biotechnology, Vol. 98, Núm. 5, pp. 2231-2241
-
PAS-LuxR transcriptional control of filipin biosynthesis in S. avermitilis
Applied Microbiology and Biotechnology, Vol. 98, Núm. 22, pp. 9311-9324
2012
-
Draft genome of Streptomyces tsukubaensis NRRL 18488, the producer of the clinically important immunosuppressant tacrolimus (FK506)
Journal of Bacteriology
-
Hierarchical control on polyene macrolide biosynthesis: PimR modulates pimaricin production via the PAS-LuxR transcriptional activator pimM
PLoS ONE, Vol. 7, Núm. 6
-
LAL regulators SCO0877 and SCO7173 as pleiotropic modulators of phosphate starvation response and actinorhodin biosynthesis in Streptomyces coelicolor
PLoS ONE, Vol. 7, Núm. 2
2011
-
Functional conservation of PAS-LuxR transcriptional regulators in polyene macrolide biosynthesis
Metabolic Engineering, Vol. 13, Núm. 6, pp. 756-767
-
Molecular control of polyene macrolide biosynthesis: Direct binding of the regulator pimm to eight promoters of pimaricin genes and identification of binding boxes
Journal of Biological Chemistry, Vol. 286, Núm. 11, pp. 9150-9161
2010
-
Structure of cytochrome P450 PimD suggests epoxidation of the polyene macrolide pimaricin occurs via a hydroperoxoferric intermediate
Chemistry and Biology, Vol. 17, Núm. 8, pp. 841-851