Juan Francisco Martín Martín-rekin lankidetzan egindako argitalpenak (27)

2012

  1. Draft genome of Streptomyces tsukubaensis NRRL 18488, the producer of the clinically important immunosuppressant tacrolimus (FK506)

    Journal of Bacteriology

  2. Hierarchical control on polyene macrolide biosynthesis: PimR modulates pimaricin production via the PAS-LuxR transcriptional activator pimM

    PLoS ONE, Vol. 7, Núm. 6

  3. LAL regulators SCO0877 and SCO7173 as pleiotropic modulators of phosphate starvation response and actinorhodin biosynthesis in Streptomyces coelicolor

    PLoS ONE, Vol. 7, Núm. 2

2011

  1. Functional conservation of PAS-LuxR transcriptional regulators in polyene macrolide biosynthesis

    Metabolic Engineering, Vol. 13, Núm. 6, pp. 756-767

  2. Molecular control of polyene macrolide biosynthesis: Direct binding of the regulator pimm to eight promoters of pimaricin genes and identification of binding boxes

    Journal of Biological Chemistry, Vol. 286, Núm. 11, pp. 9150-9161

2009

  1. PimT, an amino acid exporter controls polyene production via secretion of the quorum sensing pimaricin-inducer PI-factor in Streptomyces natalensis

    Microbial Cell Factories, Vol. 8

  2. chapter 10 Enzymology of the Polyenes Pimaricin and Candicidin Biosynthesis

    Methods in Enzymology, Vol. 459, Núm. B, pp. 215-242

2008

  1. Microbial cholesterol oxidases: Bioconversion enzymes or signal proteins?

    Molecular BioSystems, Vol. 4, Núm. 8, pp. 804-809

2007

  1. Cholesterol Oxidases Act as Signaling Proteins for the Biosynthesis of the Polyene Macrolide Pimaricin

    Chemistry and Biology, Vol. 14, Núm. 3, pp. 279-290

  2. PimM, a PAS domain positive regulator of pimaricin biosynthesis in Streptomyces natalensis

    Microbiology, Vol. 153, Núm. 9, pp. 3174-3183

  3. The two-component phoR-phoP system of Streptomyces natalensis: Inactivation or deletion of phoP reduces the negative phosphate regulation of pimaricin biosynthesis

    Metabolic Engineering, Vol. 9, Núm. 2, pp. 217-227

2006

  1. An efficient gene transfer system for the pimaricin producer Streptomyces natalensis

    FEMS Microbiology Letters, Vol. 257, Núm. 2, pp. 312-318

  2. Glycerol, ethylene glycol and propanediol elicit pimaricin biosynthesis in the PI-factor-defective strain Streptomyces natalensis npi287 and increase polyene production in several wild-type actinomycetes

    Microbiology, Vol. 152, Núm. 10, pp. 3147-3156

2005

  1. Characterization of the polyene macrolide P450 epoxidase from Streptomyces natalensis that converts de-epoxypimaricin into pimaricin

    Biochemical Journal, Vol. 386, Núm. 1, pp. 57-62

2004

  1. Characterization of the ask-asd operon in aminoethoxyvinylglycine-producing Streptomyces sp. NRRL 5331

    Applied Microbiology and Biotechnology, Vol. 64, Núm. 2, pp. 228-236

  2. Identification of PimR as a Positive Regulator of Pimaricin Biosynthesis in Streptomyces natalensis

    Journal of Bacteriology, Vol. 186, Núm. 9, pp. 2567-2575

  3. PI factor, a novel type quorum-sensing inducer elicits pimaricin production in Streptomyces natalensis

    Journal of Biological Chemistry, Vol. 279, Núm. 40, pp. 41586-41593

  4. Polyene macrolide antiobiotic biosynthesis

    Current Medicinal Chemistry, Vol. 11, Núm. 12, pp. 1645-1656

  5. Role of homoserine and threonine pathway intermediates as precursors for the biosynthesis of aminoethoxyvinylglycine in Streptomyces sp. NRRL 5331

    Microbiology, Vol. 150, Núm. 5, pp. 1467-1474

2003

  1. Domain structure characterization of the multifunctional α-aminoadipate reductase from Penicillium chrysogenum by limited proteolysis: Activation of α-aminoadipate does not require the peptidyl carrier protein box or the reduction domain

    Journal of Biological Chemistry, Vol. 278, Núm. 10, pp. 8250-8256