JESÚS MANUEL
APARICIO FERNÁNDEZ
Catedrático de Universidad
Juan Francisco
Martín Martín
Publikationen, an denen er mitarbeitet Juan Francisco Martín Martín (27)
2012
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Draft genome of Streptomyces tsukubaensis NRRL 18488, the producer of the clinically important immunosuppressant tacrolimus (FK506)
Journal of Bacteriology
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Hierarchical control on polyene macrolide biosynthesis: PimR modulates pimaricin production via the PAS-LuxR transcriptional activator pimM
PLoS ONE, Vol. 7, Núm. 6
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LAL regulators SCO0877 and SCO7173 as pleiotropic modulators of phosphate starvation response and actinorhodin biosynthesis in Streptomyces coelicolor
PLoS ONE, Vol. 7, Núm. 2
2011
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Functional conservation of PAS-LuxR transcriptional regulators in polyene macrolide biosynthesis
Metabolic Engineering, Vol. 13, Núm. 6, pp. 756-767
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Molecular control of polyene macrolide biosynthesis: Direct binding of the regulator pimm to eight promoters of pimaricin genes and identification of binding boxes
Journal of Biological Chemistry, Vol. 286, Núm. 11, pp. 9150-9161
2009
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PimT, an amino acid exporter controls polyene production via secretion of the quorum sensing pimaricin-inducer PI-factor in Streptomyces natalensis
Microbial Cell Factories, Vol. 8
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chapter 10 Enzymology of the Polyenes Pimaricin and Candicidin Biosynthesis
Methods in Enzymology, Vol. 459, Núm. B, pp. 215-242
2008
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Microbial cholesterol oxidases: Bioconversion enzymes or signal proteins?
Molecular BioSystems, Vol. 4, Núm. 8, pp. 804-809
2007
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Cholesterol Oxidases Act as Signaling Proteins for the Biosynthesis of the Polyene Macrolide Pimaricin
Chemistry and Biology, Vol. 14, Núm. 3, pp. 279-290
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PimM, a PAS domain positive regulator of pimaricin biosynthesis in Streptomyces natalensis
Microbiology, Vol. 153, Núm. 9, pp. 3174-3183
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The two-component phoR-phoP system of Streptomyces natalensis: Inactivation or deletion of phoP reduces the negative phosphate regulation of pimaricin biosynthesis
Metabolic Engineering, Vol. 9, Núm. 2, pp. 217-227
2006
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An efficient gene transfer system for the pimaricin producer Streptomyces natalensis
FEMS Microbiology Letters, Vol. 257, Núm. 2, pp. 312-318
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Glycerol, ethylene glycol and propanediol elicit pimaricin biosynthesis in the PI-factor-defective strain Streptomyces natalensis npi287 and increase polyene production in several wild-type actinomycetes
Microbiology, Vol. 152, Núm. 10, pp. 3147-3156
2005
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Characterization of the polyene macrolide P450 epoxidase from Streptomyces natalensis that converts de-epoxypimaricin into pimaricin
Biochemical Journal, Vol. 386, Núm. 1, pp. 57-62
2004
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Characterization of the ask-asd operon in aminoethoxyvinylglycine-producing Streptomyces sp. NRRL 5331
Applied Microbiology and Biotechnology, Vol. 64, Núm. 2, pp. 228-236
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Identification of PimR as a Positive Regulator of Pimaricin Biosynthesis in Streptomyces natalensis
Journal of Bacteriology, Vol. 186, Núm. 9, pp. 2567-2575
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PI factor, a novel type quorum-sensing inducer elicits pimaricin production in Streptomyces natalensis
Journal of Biological Chemistry, Vol. 279, Núm. 40, pp. 41586-41593
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Polyene macrolide antiobiotic biosynthesis
Current Medicinal Chemistry, Vol. 11, Núm. 12, pp. 1645-1656
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Role of homoserine and threonine pathway intermediates as precursors for the biosynthesis of aminoethoxyvinylglycine in Streptomyces sp. NRRL 5331
Microbiology, Vol. 150, Núm. 5, pp. 1467-1474
2003
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Domain structure characterization of the multifunctional α-aminoadipate reductase from Penicillium chrysogenum by limited proteolysis: Activation of α-aminoadipate does not require the peptidyl carrier protein box or the reduction domain
Journal of Biological Chemistry, Vol. 278, Núm. 10, pp. 8250-8256