Publications by the researcher in collaboration with ANTONIO RODRÍGUEZ GARCÍA (21)

2019

  1. Activation of secondary metabolite gene clusters in streptomyces clavuligerusby the pimm regulator of streptomyces natalensis

    Frontiers in Microbiology, Vol. 10, Núm. MAR

2018

  1. ArgR of Streptomyces coelicolor is a pleiotropic transcriptional regulator: Effect on the transcriptome, antibiotic production, and differentiation in liquid cultures

    Frontiers in Microbiology, Vol. 9, Núm. MAR

  2. Transcriptional studies on a Streptomyces clavuligerus oppA2 deletion mutant: Nacetylglycyl- clavaminic acid is an intermediate of clavulanic acid biosynthesis

    Applied and Environmental Microbiology, Vol. 84, Núm. 22

2017

  1. Discovering the potential of S. clavuligerus for bioactive compound production: Crosstalk between the chromosome and the pSCL4 megaplasmid

    BMC Genomics, Vol. 18, Núm. 1

  2. The master regulator PhoP coordinates phosphate and nitrogen metabolism, respiration, cell differentiation and antibiotic biosynthesis: Comparison in Streptomyces coelicolor and Streptomyces avermitilis

    Journal of Antibiotics, Vol. 70, Núm. 5, pp. 534-541

2015

  1. Estrategias para la activación de agrupaciones crípticas en Streptomyces clavuligerus ATCC 27064: obtención de nuevos metabolitos secundarios

    Avances en microbiología

  2. The pathway-specific regulator ClaR of Streptomyces clavuligerus has a global effect on the expression of genes for secondary metabolism and differentiation

    Applied and Environmental Microbiology, Vol. 81, Núm. 19, pp. 6637-6648

2014

  1. A 1.8-Mb-reduced Streptomyces clavuligerus genome: Relevance for secondary metabolism and differentiation

    Applied Microbiology and Biotechnology, Vol. 98, Núm. 5, pp. 2183-2195

  2. Transcriptomic analysis of Streptomyces clavuligerus ΔccaR:: Tsr: Effects of the cephamycin C-clavulanic acid cluster regulator CcaR on global regulation

    Microbial Biotechnology, Vol. 7, Núm. 3, pp. 221-231

2012

  1. ArgR of Streptomyces coelicolor is a versatile regulator

    PLoS ONE, Vol. 7, Núm. 3

2006

  1. Characterization of a two-gene operon epeRA involved in multidrug resistance in Streptomyces clavuligerus

    Research in Microbiology, Vol. 157, Núm. 6, pp. 559-568

2004

  1. Two proteins with ornithine acetyltransferase activity show different functions in Streptomyces clavuligerus: Oat2 modulates clavulanic acid biosynthesis in response to arginine

    Journal of Bacteriology, Vol. 186, Núm. 19, pp. 6501-6507

2002

  1. CcaR is an autoregulatory protein that binds to the ccaR and cefD-cmcI promoters of the cephamycin C-clavulanic acid cluster in Streptomyces clavuligerus

    Journal of Bacteriology, Vol. 184, Núm. 11, pp. 3106-3113

2000

  1. Characterization and expression of the arginine biosynthesis gene cluster of Streptomyces clavuligerus

    Journal of Molecular Microbiology and Biotechnology, Vol. 2, Núm. 4, pp. 543-550

  2. Clavulanic acid, a β-lactamase inhibitor: Biosynthesis and molecular genetics

    Applied Microbiology and Biotechnology

1999

  1. Deletion of the pyc gene blocks clavulanic acid biosynthesis except in glycerol-containing medium: Evidence for two different genes in formation of the C3 unit

    Journal of Bacteriology, Vol. 181, Núm. 22, pp. 6922-6928

1998

  1. The claR gene of Streptomyces clavuligerus, encoding a LysR-type regulatory protein controlling clavulanic acid biosynthesis, is linked to the clavulanate-9-aldehyde reductase (car) gene

    Gene, Vol. 211, Núm. 2, pp. 311-321

  2. The pcd gene encoding piperideine-6-carboxylate dehydrogenase involved in biosynthesis of α-aminoadipic acid is located in the cephamycin cluster of Streptomyces clavuligerus

    Journal of Bacteriology, Vol. 180, Núm. 17, pp. 4753-4756

1997

  1. A regulatory gene (ccaR) required for cephamycin and clavulanic acid production in Streptomyces clavuligerus: Amplification results in overproduction of both β-lactam compounds

    Journal of Bacteriology, Vol. 179, Núm. 6, pp. 2053-2059

  2. Arginine boxes and the argR gene in Streptomyces clavuligerus: Evidence for a clear regulation of the arginine pathway

    Molecular Microbiology, Vol. 25, Núm. 2, pp. 219-228