PALOMA
LIRAS PADÍN
Forscherin in der Zeit 2000-2014
ANTONIO
RODRÍGUEZ GARCÍA
PROFESOR PERMANENTE LABORAL
Publikationen, an denen er mitarbeitet ANTONIO RODRÍGUEZ GARCÍA (21)
2019
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Activation of secondary metabolite gene clusters in streptomyces clavuligerusby the pimm regulator of streptomyces natalensis
Frontiers in Microbiology, Vol. 10, Núm. MAR
2018
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ArgR of Streptomyces coelicolor is a pleiotropic transcriptional regulator: Effect on the transcriptome, antibiotic production, and differentiation in liquid cultures
Frontiers in Microbiology, Vol. 9, Núm. MAR
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Transcriptional studies on a Streptomyces clavuligerus oppA2 deletion mutant: Nacetylglycyl- clavaminic acid is an intermediate of clavulanic acid biosynthesis
Applied and Environmental Microbiology, Vol. 84, Núm. 22
2017
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Discovering the potential of S. clavuligerus for bioactive compound production: Crosstalk between the chromosome and the pSCL4 megaplasmid
BMC Genomics, Vol. 18, Núm. 1
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The master regulator PhoP coordinates phosphate and nitrogen metabolism, respiration, cell differentiation and antibiotic biosynthesis: Comparison in Streptomyces coelicolor and Streptomyces avermitilis
Journal of Antibiotics, Vol. 70, Núm. 5, pp. 534-541
2015
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Estrategias para la activación de agrupaciones crípticas en Streptomyces clavuligerus ATCC 27064: obtención de nuevos metabolitos secundarios
Avances en microbiología
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The pathway-specific regulator ClaR of Streptomyces clavuligerus has a global effect on the expression of genes for secondary metabolism and differentiation
Applied and Environmental Microbiology, Vol. 81, Núm. 19, pp. 6637-6648
2014
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A 1.8-Mb-reduced Streptomyces clavuligerus genome: Relevance for secondary metabolism and differentiation
Applied Microbiology and Biotechnology, Vol. 98, Núm. 5, pp. 2183-2195
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Transcriptomic analysis of Streptomyces clavuligerus ΔccaR:: Tsr: Effects of the cephamycin C-clavulanic acid cluster regulator CcaR on global regulation
Microbial Biotechnology, Vol. 7, Núm. 3, pp. 221-231
2012
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ArgR of Streptomyces coelicolor is a versatile regulator
PLoS ONE, Vol. 7, Núm. 3
2006
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Characterization of a two-gene operon epeRA involved in multidrug resistance in Streptomyces clavuligerus
Research in Microbiology, Vol. 157, Núm. 6, pp. 559-568
2004
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Two proteins with ornithine acetyltransferase activity show different functions in Streptomyces clavuligerus: Oat2 modulates clavulanic acid biosynthesis in response to arginine
Journal of Bacteriology, Vol. 186, Núm. 19, pp. 6501-6507
2002
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CcaR is an autoregulatory protein that binds to the ccaR and cefD-cmcI promoters of the cephamycin C-clavulanic acid cluster in Streptomyces clavuligerus
Journal of Bacteriology, Vol. 184, Núm. 11, pp. 3106-3113
2000
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Characterization and expression of the arginine biosynthesis gene cluster of Streptomyces clavuligerus
Journal of Molecular Microbiology and Biotechnology, Vol. 2, Núm. 4, pp. 543-550
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Clavulanic acid, a β-lactamase inhibitor: Biosynthesis and molecular genetics
Applied Microbiology and Biotechnology
1999
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Deletion of the pyc gene blocks clavulanic acid biosynthesis except in glycerol-containing medium: Evidence for two different genes in formation of the C3 unit
Journal of Bacteriology, Vol. 181, Núm. 22, pp. 6922-6928
1998
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The claR gene of Streptomyces clavuligerus, encoding a LysR-type regulatory protein controlling clavulanic acid biosynthesis, is linked to the clavulanate-9-aldehyde reductase (car) gene
Gene, Vol. 211, Núm. 2, pp. 311-321
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The pcd gene encoding piperideine-6-carboxylate dehydrogenase involved in biosynthesis of α-aminoadipic acid is located in the cephamycin cluster of Streptomyces clavuligerus
Journal of Bacteriology, Vol. 180, Núm. 17, pp. 4753-4756
1997
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A regulatory gene (ccaR) required for cephamycin and clavulanic acid production in Streptomyces clavuligerus: Amplification results in overproduction of both β-lactam compounds
Journal of Bacteriology, Vol. 179, Núm. 6, pp. 2053-2059
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Arginine boxes and the argR gene in Streptomyces clavuligerus: Evidence for a clear regulation of the arginine pathway
Molecular Microbiology, Vol. 25, Núm. 2, pp. 219-228