BIOLOGÍA MOLECULAR
Departamento
Irene
Santamarta Hernández
Publicaciones en las que colabora con Irene Santamarta Hernández (17)
2014
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A 1.8-Mb-reduced Streptomyces clavuligerus genome: Relevance for secondary metabolism and differentiation
Applied Microbiology and Biotechnology, Vol. 98, Núm. 5, pp. 2183-2195
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Transcriptomic analysis of Streptomyces clavuligerus ΔccaR:: Tsr: Effects of the cephamycin C-clavulanic acid cluster regulator CcaR on global regulation
Microbial Biotechnology, Vol. 7, Núm. 3, pp. 221-231
2013
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Transcriptional analysis and proteomics of the holomycin gene cluster in overproducer mutants of Streptomyces clavuligerus
Journal of Biotechnology, Vol. 163, Núm. 1, pp. 69-76
2012
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ArgR of Streptomyces coelicolor is a versatile regulator
PLoS ONE, Vol. 7, Núm. 3
2011
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A rhodanese-like protein is highly overrepresented in the mutant S. clavuligerus oppA2::aph: Effect on holomycin and other secondary metabolites production
Microbial Biotechnology, Vol. 4, Núm. 2, pp. 216-225
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Characterization of DNA-binding sequences for CcaR in the cephamycin-clavulanic acid supercluster of Streptomyces clavuligerus
Molecular Microbiology, Vol. 81, Núm. 4, pp. 968-981
2010
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Morphological differentiation and clavulanic acid formation are affected in a Streptomyces clavuligerus adpA-deleted mutant
Microbiology, Vol. 156, Núm. 8, pp. 2354-2365
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The enigmatic lack of glucose utilization in Streptomyces clavuligerus is due to inefficient expression of the glucose permease gene
Microbiology, Vol. 156, Núm. 5, pp. 1527-1537
2008
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Regulatory mechanisms controlling antibiotic production in Streptomyces clavuligerus
Journal of Industrial Microbiology and Biotechnology, Vol. 35, Núm. 7, pp. 667-676
2007
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Caracterización de la función de AreB sobre la biosíntesis de leucina y la producción de cefamicina C y ácido clavulánico en Streptomyces clavuligerus
SEG 2007: libro de resúmenes
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Connecting primary and secondary metabolism: AreB, an IclR-like protein, binds the AREccaR sequence of S. clavuligerus and modulates leucine biosynthesis and cephamycin C and clavulanic acid production
Molecular Microbiology, Vol. 66, Núm. 2, pp. 511-524
2006
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Characterization of a two-gene operon epeRA involved in multidrug resistance in Streptomyces clavuligerus
Research in Microbiology, Vol. 157, Núm. 6, pp. 559-568
2005
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Different proteins bind to the butyrolactone receptor protein ARE sequence located upstream of the regulatory ccaR gene of Streptomyces clavuligerus
Molecular Microbiology, Vol. 56, Núm. 3, pp. 824-835
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Erratum: Different proteins bind to the butyrolactone receptor protein ARE sequence located upstream of the regulatory ccaR gene of Streptomyces clavuligerus (Molecular Microbiology (2005) 56 (824-835))
Molecular Microbiology
2004
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Two oligopeptide-permease-encoding genes in the clavulanic acid cluster of Streptomyces clavuligerus are essential for production of the β-lactamase inhibitor
Journal of Bacteriology, Vol. 186, Núm. 11, pp. 3431-3438
2002
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CcaR is an autoregulatory protein that binds to the ccaR and cefD-cmcI promoters of the cephamycin C-clavulanic acid cluster in Streptomyces clavuligerus
Journal of Bacteriology, Vol. 184, Núm. 11, pp. 3106-3113
2001
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Structure of the ask-asd operon and formation of aspartokinase subunits in the cephamycin producer 'Amycolatopsis lactamdurans'
Microbiology, Vol. 147, Núm. 6, pp. 1547-1555