Publicaciones en las que colabora con Christopher Fernández Prada (12)

2015

  1. Trypanosomatids see the light: Recent advances in bioimaging research

    Drug Discovery Today, Vol. 20, Núm. 1, pp. 114-121

2014

  1. Trypanosomatids topoisomerase re-visited. New structural findings and role in drug discovery

    International Journal for Parasitology: Drugs and Drug Resistance, Vol. 4, Núm. 3, pp. 326-337

2013

  1. Gimatecan and other camptothecin derivatives poison Leishmania DNA-topoisomerase IB leading to a strong leishmanicidal effect

    Biochemical Pharmacology, Vol. 85, Núm. 10, pp. 1433-1440

  2. Identification and characterization of the regions involved in the nuclear translocation of the heterodimeric leishmanial DNA topoisomerase IB.

    PloS one, Vol. 8, Núm. 9

  3. Synthesis of marine α-methoxylated fatty acid analogs that effectively inhibit the topoisomerase IB from leishmania donovani with a mechanism different from that of camptothecin

    Marine Drugs, Vol. 11, Núm. 10, pp. 3661-3675

2012

  1. 2-Alkynoic fatty acids inhibit topoisomerase IB from Leishmania donovani

    Bioorganic and Medicinal Chemistry Letters, Vol. 22, Núm. 19, pp. 6185-6189

  2. A pentapeptide signature motif plays a pivotal role in Leishmania DNA topoisomerase IB activity and camptothecin sensitivity

    Biochimica et Biophysica Acta - General Subjects, Vol. 1820, Núm. 12, pp. 2062-2071

  3. Appraisal of a Leishmania major Strain Stably Expressing mCherry Fluorescent Protein for Both In Vitro and In Vivo Studies of Potential Drugs and Vaccine against Cutaneous Leishmaniasis

    PLoS Neglected Tropical Diseases, Vol. 6, Núm. 11

  4. First total synthesis of the (±)-2-methoxy-6-heptadecynoic acid and related 2-methoxylated analogs as effective inhibitors of the Leishmania topoisomerase IB enzyme

    Pure and Applied Chemistry, Vol. 84, Núm. 9, pp. 1867-1875

  5. Indotecan (LMP400) and AM13-55: Two novel indenoisoquinolines show potential for treating visceral leishmaniasis

    Antimicrobial Agents and Chemotherapy, Vol. 56, Núm. 10, pp. 5264-5270

  6. Role of trypanosomatid's arginase in polyamine biosynthesis and pathogenesis

    Molecular and Biochemical Parasitology, Vol. 181, Núm. 2, pp. 85-93

2009

  1. Novel findings on trypanosomatid chemotherapy using DNA topoisomerase inhibitors

    Mini-Reviews in Medicinal Chemistry, Vol. 9, Núm. 6, pp. 674-686