JOSÉ MANUEL
FERNÁNDEZ CAÑÓN
PROFESOR CONTRATADO DOCTOR
Publications (27) JOSÉ MANUEL FERNÁNDEZ CAÑÓN publications
2023
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Biotecnología Microbiana de origen bioquímico
SEM@foro, Núm. 76, pp. 30-33
2019
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Identification and expression of the 11β-steroid hydroxylase from Cochliobolus lunatus in Corynebacterium glutamicum
Microbial Biotechnology, Vol. 12, Núm. 5, pp. 856-868
2017
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Steroid 11-alpha-hydroxylation by the fungi Aspergillus nidulans and Aspergillus ochraceus
Methods in Molecular Biology (Humana Press Inc.), pp. 271-287
2008
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Activation of nuclear factor E2-related factor 2 in hereditary tyrosinemia type 1 and its role in survival and tumor development
Hepatology, Vol. 48, Núm. 2, pp. 487-496
2007
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Novel phacB-encoded cytochrome P450 monooxygenase from Aspergillus nidulans with 3-hydroxyphenylacetate 6-hydroxylase and 3,4-dihydroxyphenylacetate 6-hydroxylase activities
Eukaryotic Cell, Vol. 6, Núm. 3, pp. 514-520
2003
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Pharmacologic or genetic ablation of maleylacetoacetate isomerase increases levels of toxic tyrosine catabolites in rodents
Biochemical Pharmacology, Vol. 66, Núm. 10, pp. 2029-2038
2002
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Maleylacetoacetate isomerase (MAAI/GSTZ)-deficient mice reveal a glutathione-dependent nonenzymatic bypass in tyrosine catabolism
Molecular and Cellular Biology, Vol. 22, Núm. 13, pp. 4943-4951
2001
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Reduced function of a phenylacetate-oxidizing cytochrome P450 caused strong genetic improvement in early phylogeny of penicillin-producing strains
Journal of Bacteriology, Vol. 183, Núm. 19, pp. 5465-5471
1999
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Disruption of phacA, an Aspergillus nidulans gene encoding a novel cytochrome P450 monooxygenase catalyzing phenylacetate 2-hydroxylation, results in penicillin overproduction
Journal of Biological Chemistry, Vol. 274, Núm. 21, pp. 14545-14550
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Gene structure, chromosomal location, and expression pattern of maleylacetoacetate isomerase
Genomics, Vol. 58, Núm. 3, pp. 263-269
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Identification of the mutation in the alkaptonuria mouse model. Mutations in brief no. 216. Online.
Human mutation, Vol. 13, Núm. 2, pp. 171
1998
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Characterization of a fungal maleylacetoacetate isomerase gene and identification of its human homologue
Journal of Biological Chemistry, Vol. 273, Núm. 1, pp. 329-337
1997
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Spectrophotometric determination of homogentisate using Aspergillus nidulans homogentisate dioxygenase
Analytical Biochemistry, Vol. 245, Núm. 2, pp. 218-221
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The human homogentisate 1,2-dioxygenase (HGO) gene
Genomics, Vol. 43, Núm. 2, pp. 115-122
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The phenylacetic acid uptake system of Aspergillus nidulans is under a creA-independent model of catabolic repression which seems to be mediated by acetyl-CoA
Journal of Antibiotics, Vol. 50, Núm. 1, pp. 45-52
1996
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The molecular basis of alkaptonuria
Nature Genetics, Vol. 14, Núm. 1, pp. 19-24
1995
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Carbon regulation of penicillin biosynthesis in Aspergillus nidulans: A minor effect of mutations in creB and creC
FEMS Microbiology Letters, Vol. 126, Núm. 1, pp. 63-67
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Fungal metabolic model for human type I hereditary tyrosinaemia
Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Núm. 20, pp. 9132-9136
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Molecular characterization of a gene encoding a homogentisate dioxygenase from Aspergillus nidulans and identification of its human and plant homologues
Journal of Biological Chemistry, Vol. 270, Núm. 36, pp. 21199-21205
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Overexpression of two penicillin structural genes in Aspergillus nidulans
Mgg Molecular & General Genetics, Vol. 246, Núm. 1, pp. 110-118