PALOMA
LIRAS PADÍN
Investigador/a no período 2000-2014
![Foto de Juan Francisco](/img/nophoto.png)
Juan Francisco
Martín Martín
Publicacións nas que colabora con Juan Francisco Martín Martín (56)
2023
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Insights into the molecular mechanisms of β-lactam antibiotic synthesizing and modifying enzymes in fungi
Biotechnology of Microbial Enzymes: Production, Biocatalysis, and Industrial Applications, Second Edition (Elsevier), pp. 199-228
2018
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Transcriptional studies on a Streptomyces clavuligerus oppA2 deletion mutant: Nacetylglycyl- clavaminic acid is an intermediate of clavulanic acid biosynthesis
Applied and Environmental Microbiology, Vol. 84, Núm. 22
2017
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The master regulator PhoP coordinates phosphate and nitrogen metabolism, respiration, cell differentiation and antibiotic biosynthesis: Comparison in Streptomyces coelicolor and Streptomyces avermitilis
Journal of Antibiotics, Vol. 70, Núm. 5, pp. 534-541
2015
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A natural short pathway synthesizes roquefortine C but not meleagrin in three different Penicillium roqueforti strains
Applied Microbiology and Biotechnology, Vol. 99, Núm. 18, pp. 7601-7612
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Molecular genetics of naringenin biosynthesis, a typical plant secondary metabolite produced by Streptomyces clavuligerus
Microbial Cell Factories, Vol. 14, Núm. 1
2014
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A 1.8-Mb-reduced Streptomyces clavuligerus genome: Relevance for secondary metabolism and differentiation
Applied Microbiology and Biotechnology, Vol. 98, Núm. 5, pp. 2183-2195
2013
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Expression of the endogenous and heterologous clavulanic acid cluster in Streptomyces flavogriseus: Why a silent cluster is sleeping
Applied Microbiology and Biotechnology, Vol. 97, Núm. 21, pp. 9451-9463
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Transcriptional analysis and proteomics of the holomycin gene cluster in overproducer mutants of Streptomyces clavuligerus
Journal of Biotechnology, Vol. 163, Núm. 1, pp. 69-76
2012
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ArgR of Streptomyces coelicolor is a versatile regulator
PLoS ONE, Vol. 7, Núm. 3
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Cascades and networks of regulatory genes that control antibiotic biosynthesis
Subcellular Biochemistry, Vol. 64, pp. 115-138
2011
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A rhodanese-like protein is highly overrepresented in the mutant S. clavuligerus oppA2::aph: Effect on holomycin and other secondary metabolites production
Microbial Biotechnology, Vol. 4, Núm. 2, pp. 216-225
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Characterization of DNA-binding sequences for CcaR in the cephamycin-clavulanic acid supercluster of Streptomyces clavuligerus
Molecular Microbiology, Vol. 81, Núm. 4, pp. 968-981
2010
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Engineering of regulatory cascades and networks controlling antibiotic biosynthesis in Streptomyces
Current Opinion in Microbiology, Vol. 13, Núm. 3, pp. 263-273
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The enigmatic lack of glucose utilization in Streptomyces clavuligerus is due to inefficient expression of the glucose permease gene
Microbiology, Vol. 156, Núm. 5, pp. 1527-1537
2009
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β-Lactam Antibiotics
Encyclopedia of Microbiology (Elsevier Inc.), pp. 274-289
2008
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Streptomyces clavuligerus relA-null mutants overproduce clavulanic acid and cephamycin C: Negative regulation of secondary metabolism by (p)ppGpp
Microbiology, Vol. 154, Núm. 3, pp. 744-755
2007
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Connecting primary and secondary metabolism: AreB, an IclR-like protein, binds the AREccaR sequence of S. clavuligerus and modulates leucine biosynthesis and cephamycin C and clavulanic acid production
Molecular Microbiology, Vol. 66, Núm. 2, pp. 511-524
2006
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An rplKΔ29-PALG-32 mutation leads to reduced expression of the regulatory genes ccaR and claR and very low transcription of the ceaS2 gene for clavulanic acid biosynthesis in Streptomyces clavuligerus
Molecular Microbiology, Vol. 61, Núm. 3, pp. 758-770
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Characterization of a two-gene operon epeRA involved in multidrug resistance in Streptomyces clavuligerus
Research in Microbiology, Vol. 157, Núm. 6, pp. 559-568
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Characterization of an hyperpigmenting mutant of Monascus purpureus IB1: Identification of two novel pigment chemical structures
Applied Microbiology and Biotechnology, Vol. 70, Núm. 4, pp. 488-496