Publications by the researcher in collaboration with JUAN JOSÉ RUBIO COQUE (14)

1998

  1. The nine genes of the Nocardia lactamdurans cephamycin cluster are transcribed into large mRNAs from three promoters, two of them located in a bidirectional promoter region

    Journal of Bacteriology, Vol. 180, Núm. 20, pp. 5489-5494

1997

  1. The bla gene of the cephamycin cluster of Streptomyces clavuligerus encodes a class A β-lactamase of low enzymatic activity

    Journal of Bacteriology, Vol. 179, Núm. 19, pp. 6035-6040

1996

  1. Characterization of the cefF gene of Nocardia lactamdurans encoding a 3′-methylcephem hydroxylase different from the 7-cephem hydroxylase

    Applied Microbiology and Biotechnology, Vol. 44, Núm. 5, pp. 605-609

  2. Overexpression of the Nocardia lactamdurans α-aminoadipyl-cysteinyl-valine synthetase in Streptomyces lividans. The purified multienzyme uses cystathionine and 6-oxopiperidine 2-carboxylate as substrates for synthesis of the tripeptide

    European Journal of Biochemistry, Vol. 242, Núm. 2, pp. 264-270

1995

  1. A two-protein component 7α-cephem-methoxylase encoded by two genes of the cephamycin C cluster converts cephalosporin C to 7-methoxycephalosporin C

    Journal of Bacteriology, Vol. 177, Núm. 8, pp. 2230-2235

  2. Characterization of the cmcH genes of Nocardia lactamdurans and streptomyces clavuligerus encoding a functional 3'-hydroxymethylcephem O-carbamoyltransferase for cephamycin biosynthesis

    Gene, Vol. 162, Núm. 1, pp. 21-27

1994

  1. Grouping of the genes of biosynthesis and resistance to beta-lactam antibiotics in cephamycin-C producing actinomycetes

    Microbiología (Madrid, Spain), Vol. 10, Núm. 1-2, pp. 49-56

  2. Interdependence of Gene Expression for Early Steps of Cephalosporin Synthesis in Streptomyces clavuligerus

    Annals of the New York Academy of Sciences, Vol. 721, Núm. 1, pp. 117-122

  3. Possible involvement of the lysine ε-aminotransferase gene (lat) in the expression of the genes encoding ACV synthetase (pcbAB) and isopenicillin N synthase (pcbC) in Streptomyces clavuligerus

    Microbiology, Vol. 140, Núm. 12, pp. 3367-3377

1993

  1. Analysis of the codon usage of the cephamycin C producer Nocardia lactamdurans

    FEMS Microbiology Letters, Vol. 110, Núm. 1, pp. 91-95

  2. Characterization and expression in Streptomyces lividans of cefD and cefE genes from Nocardia lactamdurans: the organization of the cephamycin gene cluster differs from that in Streptomyces clavuligerus

    MGG Molecular & General Genetics, Vol. 236, Núm. 2-3, pp. 453-458

  3. Genes for a β-lactamase, a penicillin-binding protein and a transmembrane protein are clustered with the cephamycin biosynthetic genes in Nocardia lactamdurans

    EMBO Journal, Vol. 12, Núm. 2, pp. 631-639

1991

  1. A gene encoding lysine 6-aminotransferase, which forms the β-lactam precursor α-aminoadipic acid, is located in the cluster of cephamycin biosynthetic genes in Nocardia lactamdurans

    Journal of Bacteriology, Vol. 173, Núm. 19, pp. 6258-6264

  2. The cephamycin biosynthetic genes pcbAB, encoding a large multidomain peptide synthetase, and pcbC of Nocardia lactamdurans are clustered together in an organization different from the same genes in Acremonium chrysogenum and Penicillium chrysogenum

    Molecular Microbiology, Vol. 5, Núm. 5, pp. 1125-1133