Infección experimental de corderos con diferentes cepas de mycobacterium avium subespecie paratuberculosis

  1. A. Verna
  2. M. Muñoz
  3. O. Moreno 1
  4. C. García Pariente 1
  5. M.V. Geijo
  6. L.E. Reyes 1
  7. R.A. Juste
  8. F. Paolichi
  9. M.I. Romano
  10. J.F. García Marín 1
  11. V. Pérez 1
  1. 1 Universidad de León
    info

    Universidad de León

    León, España

    ROR https://ror.org/02tzt0b78

Book:
Producción Ovina y Caprina: XXIX Jornadas Científicas. VIII Internacionales de la Sociedad Española de Ovinotecnia y Caprinotecnia
  1. Fernando Forcada Miranda (coord.)
  2. Eduardo Angulo Asensio (coord.)
  3. José Antonio García de Jalón Ciércoles (coord.)
  4. Marcelo de las Heras Guillamón (coord.)
  5. Fernando López Gatius (coord.)
  6. Marianao Domingo Álvarez (coord.)
  7. Alfonso Abecia Martínez (coord.)

Publisher: Sociedad Española de Ovinotecnia y Caprinotecnia SEOC

Year of publication: 2004

Congress: Sociedad Española de Ovinotecnia y Caprinotecnia (SEOC). Jornadas (8. 2004. Lleida)

Type: Conference paper

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Abstract

In order to know the pathogenicity of several Map strains and their ability to infect different animalspecies, an oral experimental infection has been carried out in 30 lambs, divided in 6 groups, infected asfollows: (a) bovine strain, directly isolated from the intestinal mucosa of a clinical case; (b) the same strain afterbeing growth in laboratory media; (c, d) two bovine strains from Argentina, with different genetic pattern; (e)ovine strain purified from the intestinal mucosa; (f) control. Cellular and humoral immune responses wereassessed, as well as the presence of Map DNA in blood by PCR, along 5 mpi. At this time, lambs were killedand pathological and microbiological studies performed in tissue samples. All the strains were able to infect theanimals but differences in the responses were observed. Lesions induced by the ovine strain were most severe.

Data source: Dialnet