Insuficiencia renal aguda experimental por aminoglucosidosefecto sobre el metabolismo fosfocalcico

  1. M. Inmaculada Diez Prieto
  2. Carlos César Pérez García
  3. Juan Rejas López
  4. Ángel Javier Alonso Díez
  5. Paulino García Partida
Journal:
Revista de toxicología

ISSN: 0212-7113

Year of publication: 1990

Volume: 7

Issue: 1

Pages: 5-12

Type: Article

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Abstract

We have evaluated the effect of the nephrotoxic acute renal failure (neomycin sulphate, 100 mg/kg bodyweight) on the calcium and phosphorus metabolism. We have found higher levéisin urea (1,33 g/i), increatinine (7,97 mg/dl), and serical phosphorus (14,43 mg/dl); we have also noticed some increases (though lower) in magnesemia (2,75 mg/dl), in proteinemia (7,15 g/l) and in the activity of alkaline phosphatase (71,25 Ul/I); the calcemia, onthe contrary, hada remarkable decrease (7,81 mg/dl), similar at the hydroxyprolinuria (15,75mg/24 h) but without stadistíc significance, in this case.

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