Insuficiencia renal aguda experimental por aminoglucosidosefecto sobre el metabolismo fosfocalcico

  1. M. Inmaculada Diez Prieto
  2. Carlos César Pérez García
  3. Juan Rejas López
  4. Ángel Javier Alonso Díez
  5. Paulino García Partida
Revista de toxicología

ISSN: 0212-7113

Year of publication: 1990

Volume: 7

Issue: 1

Pages: 5-12

Type: Article

More publications in: Revista de toxicología


Cited by

  • Scopus Cited by: 0 (12-09-2023)


We have evaluated the effect of the nephrotoxic acute renal failure (neomycin sulphate, 100 mg/kg bodyweight) on the calcium and phosphorus metabolism. We have found higher levéisin urea (1,33 g/i), increatinine (7,97 mg/dl), and serical phosphorus (14,43 mg/dl); we have also noticed some increases (though lower) in magnesemia (2,75 mg/dl), in proteinemia (7,15 g/l) and in the activity of alkaline phosphatase (71,25 Ul/I); the calcemia, onthe contrary, hada remarkable decrease (7,81 mg/dl), similar at the hydroxyprolinuria (15,75mg/24 h) but without stadistíc significance, in this case.