Validez interna de una prueba rápida de detección de antígenos COVID-19 en una residencia de mayores

  1. C. Diez Flecha 1
  2. A.M. Rivero Rodríguez 1
  3. T. Fernández-Villa 2
  4. P. Fernández García 3
  5. J.L. Ferreira de Jesús 1
  6. G. Sánchez Antolín 4
  1. 1 Gerencia de Atención Primaria de León, León, España
  2. 2 Grupo de Investigación en Interacciones Gen-Ambiente-Salud (GIIGAS), Instituto de Biomedicina (IBIOMED), Universidad de León, León, España
  3. 3 Complejo Asistencial Universitario de León, León, España
  4. 4 Sanidad de Castilla y León (SACYL), Junta de Castilla y León, Valladolid, España
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Revista:
Semergen: revista española de medicina de familia

ISSN: 1138-3593

Año de publicación: 2021

Número: 5

Páginas: 332-336

Tipo: Artículo

DOI: 10.1016/J.SEMERG.2021.04.003 DIALNET GOOGLE SCHOLAR

Otras publicaciones en: Semergen: revista española de medicina de familia

Objetivos de desarrollo sostenible

Resumen

Introduction RT-qPCR is the reference test for the detection of SARS-CoV-2 infection, however, rapid antigen detection tests (RADT) are now available. In this work, the internal validity of the RADT was evaluated in the context of an outbreak in a nursing home. Methods Nasopharyngeal exudate samples were analyzed by RADT and RT-qPCR from 61 residents of a nursing home. The sensitivity and specificity of RADT with respect to RT-qPCR was calculated. Results Specificity was 100% (95% CI 54.1-100.0), while sensitivity in asymptomatic people was 70.3% (95% CI 53.0-84.1) and in symptomatic people 83.3% (95% CI 51.6-97.9). Conclusions The RADTs are sufficiently sensitive and specific to be used as screening tests in nursing homes, especially in situations of outbreaks or suspected outbreaks due to the presence of symptoms.

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Fuente de los datos: Dialnet