Seguridad de la ivermectinatoxicidad y reacciones adversas en diversas especies de mamíferos
- González Canga, Aranzazu
- Fernández Martínez, María Nélida
- Sahagún Prieto, Ana María
- García Vieitez, Juan José
- Díez Liébana, María José
- Tamame-Martín, Pedro Pablo
- Sierra Vega, Matilde
ISSN: 1909-0544, 0122-0268
Année de publication: 2010
Volumen: 15
Número: 2
Pages: 2127-2135
Type: Article
D'autres publications dans: Revista MVZ Córdoba
Résumé
The antiparasitic drug Ivermectin is frequently used in veterinary medicine, due to its broad spectrum of activity (both against endo- and ectoparasites, high efficacy and wide margin of safety. However, its administration can give rise to toxic effects. Most of them come from the overdosage of the compound, although, at therapeutic doses, it also has been described an increased susceptibility to Ivermectin toxicosis in some breeds and subpopulations of animals, as well as severe anaphylactic reactions due to the sudden massive release of parasite toxins.