Farmacocinética clínica del levamisol en el conejo. Iadministración oral

  1. Díez Liébana, María José
  2. Terán, M. Teresa
  3. García Vieitez, Juan José
  4. Sierra Vega, Matilde
Revista:
Anales de la Facultad de Veterinaria de León

ISSN: 0373-1170

Any de publicació: 1989

Any: 35

Número: 35

Pàgines: 63-69

Tipus: Article

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Altres publicacions en: Anales de la Facultad de Veterinaria de León

Resum

The absortion of levamisole was studied in fifteen New Zealand white rabbits after oral administration of 12.5; 16 and 20 mg/kg. The plasma levels of unaltered levamisole were determinated by high pressure liquid chromatography and fitted according to a two-compartment model. Peak plasma experimental levels of levamisole, 0.68, 1.12 and 1.50 pg/ml, were observed at 30, 60 and 60 minutes respectively after dosing. This fact indicates a moderate absortion rate of orally administered levamisole.

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