Intervención para la mejora del conocimiento de los factores de riesgo para el desarrollo de osteonecrosis maxilar en pacientes a tratamiento con bisfosfonatos. Ensayo clínico aleatorizado

  1. Lucía García-Martínez
  2. Rubén Martín-Payo
  3. Alejandro Pelaz-García
  4. Matilde Sierra-Vega
  5. Luis Manuel Junquera-Gutiérrez
Revista:
Enfermería clínica

ISSN: 1130-8621

Any de publicació: 2017

Volum: 27

Número: 6

Pàgines: 352-360

Tipus: Article

DOI: 10.1016/J.ENFCLI.2017.04.001 DIALNET GOOGLE SCHOLAR

Altres publicacions en: Enfermería clínica

Resum

Purpose To evaluate the effectiveness of a health education programme on knowledge and reduction of the risk factors for bisphosphonate-related osteonecrosis of the jaw. Methods An experimental study control group without intervention was performed with 60 subjects who had started treatment with bisphosphonates in the University Hospital of León from October to December 2014. Patients in the experimental group received a structured education intervention in two sessions. The data was collected from a heteroadministered questionnaire at the beginning and at the end of the study period for both groups. Results The educational intervention designed showed a significantly increased adherence to healthy behaviours related to oral hygiene such as mechanical control of plaque and the use of clorhexidine prior to invasive oral procedures. All subjects reported that they had not been advised to maintain a good level of oral health before starting treatment. After the intervention high percentages of recognition of early diagnostic measures starting from a baseline total ignorance of them were determined. No conclusive information about the use of removable dental prostheses, toxic habits or maintaining proper metabolic control in patients with diabetes mellitus was observed. Conclusions Improving adherence to healthy behaviours related to oral health following the intervention, as well as their contribution to the early identification of warning signs of jaw osteonecrosis, stresses the importance of the use of health education as a tool in routine clinical practice.

Referències bibliogràfiques

  • Marx, R.E., Oral and Intravenous Bisphosphonate-Induced Osteonecrosis of the Jaws. History, Etiology, Prevention and Treatment. 2nd edition, 2011, Quintessence Publishing, Canada.
  • Ponte Fernández, N., Estefanía Fresco, R., Aguirre Urizar, J.M., Biphosphonates and oral pathology I. General and preventive aspects. Med Oral. 11 (2006), E396–E400.
  • Russo Dello, N.M., Jeffcoat, M.K., Marx, R.E., Fugazzotto, P., Osteonecrosis in the jaws of patients who are using oral biphosphonates to treat osteoporosis. Int J Oral Maxillofac Implants. 22 (2007), 146–153.
  • Hollingworth, S.A., Gunanti, I., Nissen, L.M., Duncan, E.L., Secondary prevention of osteoporosis in Australia: Analysis of government-dispensed prescription data. Drugs Aging. 27 (2010), 255–264.
  • Ruggiero, S.L., Fantasia, J., Carlson, E., Biphosphonate-related osteonecrosis of the jaw: Background and guidelines for diagnosis, staging and management. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 102 (2006), 433–441.
  • Del Castillo Pardo de Vera, J.L., de Marcos, J.A.G., Rodriguez, S.A., Arenas, M.G., Polanco, J.C., Osteonecrosis de los maxilares asociada al empleo de bifosfonatos. Rev Esp Cirug Oral y Maxilofac. 29 (2007), 295–308.
  • Junquera, L., Gallego, L., Cuesta, P., Pelaz, A., de Vicente, J.C., Clinical experiences with bisphosphonate-associated osteonecrosis of the jaws: Analysis of 21 cases. Am J Otolaryngol 30 (2009), 390–395.
  • Erviti, J., Drugs prescription for osteoporosis. An Sist Sanit Navar. 26:Supl 3 (2003), 107–121.
  • Ruggiero, S.L., Dodson, T.B., Assael, L.A., Landesberg, R., Marx, R.E., Mehrotra, B., American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws—2009 update. J Oral Maxillofac Surg. 67:5 Suppl (2009), 2–12.
  • Lo, J.C., O'Ryan, F.S., Gordon, N.P., Yang, J., Hui, R.L., Martin, D., et al. Investigators PROOOTJWOBEP. Prevalence of osteonecrosis of the jaw in patients with oral bisphosphonate exposure. J Oral Maxillofac Surg. 68 (2010), 243–253.
  • Filleul, O., Crompot, E., Saussez, S., Biphosphonate-induced osteonecrosis of the jaw: A review of 2,400 patient cases. J Cancer Res Clin Oncol. 136 (2010), 1117–1124.
  • Williams, K., Ferrante, A., Dockter, K., Haun, J., Biesbrock, A.R., Bartizek, R.D., One- and 3-minute plaque removal by a battery-powered versus a manual toothbrush. J Periodontol. 75 (2004), 1107–1113.
  • Bonacina, R., Mariani, U., Villa, F., Villa, A., Preventive strategies and clinical implications for biphosphonate-related osteonecrosis of the jaw: Review of 282 patients. J Can Dent Assoc., 77, 2011, b147.
  • Slade, G.D., Spencer, A.J., Development and evaluation of the oral health impact profile. Community Dent Health. 11 (1994), 3–11.
  • World Health Organization. Diet, nutrition and the prevention of chronic diseases. World Health Organ Tech Rep Ser., 196, 2003 I-VIII-1-149-backover.
  • Junquera, L.M., Martin-Granizo, R., Diagnóstico, prevención y tratamiento de la osteonecrosis de los maxilares por bisfosfonatos. Recomendaciones de la Sociedad Española de Cirugía Oral y Maxilofacial (SECOM). Rev Esp Cir Oral Y Maxilofac. 30 (2008), 145–156.
  • Sambunjak, D., Nickerson, J.W., Poklepovic, T., Johnson, T.M., Imai, P., Tugwell, P., et al. Flossing for the management of periodontal diseases and dental caries in adults. Cochrane Database Syst Rev., 2011, CD008829.
  • Watt, R.G., New W.H.O. diet and nutrition review: Implications for dental disease prevention. Nutrition. 19:11-12 (2003), 1028–1029.
  • Rizzoli, R., Reginster, J.-Y., Boonen, S., Bréart, G., Diez-Perez, A., Felsenberg, D., et al. Adverse reactions and drug-drug interactions in the management of women with postmenopausal osteoporosis. Calcif Tissue Int. 89 (2011), 91–104.
  • Hewitt, R.E., Lissina, A., Green, A.E., Slay, E.S., Price, D.A., Sewell, A.K., The bisphosphonate acute phase response: Rapid and copious production of proinflammatory cytokines by peripheral blood gd T cells in response to aminobisphosphonates is inhibited by statins. Clin Exp Immunol. 139 (2005), 101–111.
  • Ruggiero, S.L., Dodson, T.B., Fantasia, J., Goodday, R., Aghaloo, T., Mehrotra, B., et al., American Association of Oral and Maxillofacial Surgeons. American Association of Oral and Maxillofacial Surgeons position paper on medication-related osteonecrosis of the jaw—2014 update. J Oral Maxillofac Surg. 72 (2014), 1938–1956.
  • Bocanegra-Pérez, S., Limiñana-Cañal, J.M., Vicente-Barrero, M., Sosa-Henríquez, M., Graziani-González, R., Pérez Ávila, B., et al. Bisfosfonatos en atención primaria. Estudio epidemiológico de la administración y repercusión de bisfosfonatos en pacientes que acuden a consultas de odontología del Servicio Canario de Salud. Av Odontoestomatol. 26 (2010), 143–151.
  • Heras Roncón, I., Zubillaga Rodríguez, I., Castrillo Tambay, M., Montalvo Moreno, J.J., Osteonecrosis of the jaws and bisphosphonates. Report of fifteen cases. Therapeutic recommendations. Med Oral. 12 (2007), E67–E71.
  • Russell, M.A.H., Wilson, C., Taylor, C., Baker, C.D., Effect of general practitioners’ advice against smoking. Br Med J. 2 (1979), 231–235.
  • Chakkalakal, D.A., Alcohol-induced bone loss and deficient bone repair. Alcohol Clin Exp Res. 29 (2005), 2077–2090.
  • Sosa Henríquez, M., Gómez de Tejada Romero, Bagan Sebastián, J.V., Días Curial, M., Dias Pérez, A., Jedar Gimeno, E., et al. Osteonecrosis de los maxilares: Documento de consenso. Rev Osteoporos Metab Miner. 1 (2009), 41–51.
  • AsturSalud: Portal de Salud del Principado de Asturias [Internet]. Principado de Asturias: Consejería de Salud y Servicios Sociales del Principado de Asturias; c2006 [citado 10 May 2016]. www.astursalud.es 1-154. Disponible en: http://www.asturias.es/Astursalud/Articulos/AS–S20Publica/ASSalud%20Poblacional/Salud%20bucodental/LIBRO BUCODENTAL.pdf.
  • De Sarro, A., Minutoli, L., Pharmacology: Mechanism of Action of Bisphoshonates. Saverio de Ponte, F., (eds.) Bisphosphonates and Osteonecrosis of the Jaw. A Multidisciplinary Approach, 1st ed., 2012, Springer, 13–21.
  • Turner, B., Ali, S., Pati, J., Nargund, V., Ali, E., Cheng, L., et al. Retrospective audit: Does prior assessment by oral and maxillofacial surgeons reduce the risk of osteonecrosis of the jaw in patients receiving bone-targeted therapies for metastatic cancers to the skeleton? — Part II. Urol Nurs. 36 (2016), 117–122 132.
  • Qian, Y., Arellano, J., Hauber, A.B., Mohamed, A.F., Gonzalez, J.M., Hechmati, G., et al. Patient, caregiver, and nurse preferences for treatments for bone metastases from solid tumors. Patient 9 (2016), 323–333.
Fuente de los datos: Dialnet